Figure 7
From: Impact of protein O-GlcNAcylation on neural tube malformation in diabetic embryopathy
Effects of OGT inhibition on ER stress and apoptosis. Immunoblot assay of protein expression in the neural tissues of E10.5 embryos from non-diabetic (ND), diabetic-vehicle (DM-VEH), and diabetic-ST045849 (DM-ST; 20  mg/kg, daily, from E6.5 to E9.5) groups. (A) Immunoblots. β-actin, loading control. (B,C) Quantification of the immunoblot bands. Data are presented as mean ± SD. n = 3 embryos from 3 litters. Full-length blots of Chop and Casp3 are included in the Supplementary Information (Figure S3).
