Table 4 Summary Statistics for Mutation Analysis.

From: Electroretinography Reveals Difference in Cone Function between Syndromic and Nonsyndromic USH2A Patients

 

Syndromic

Nonsyndromic

Odds ratio (CI)

P Value

N number

10

10

  

Males, Females

6, 4

5, 5

  

Age (mean ± SD)

33 ± 14

44 ± 16

 

p = 0.16

% of Patients with indels or nonsense mutations

70 (7/10)

30 (3/10)

6.4 (0.5, 128)

p = 0.09†

% of Alleles with indels or nonsense mutations

45 (9/20)

15 (3/20)

4.6 (1.1, 20)

p = 0.04‡

  1. †Determined by Fisher’s exact test. ‡Determined by logistic regression models. Indel; insertion or deletion leading to an out-of-frame shift.
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