Figure 5
From: Maternal diabetes causes developmental delay and death in early-somite mouse embryos
Pathway analysis of differences in gene expression between control and retarded or non-retarded experimental embryos. Non-retarded ED8.5 experimental embryos were compared to 1-day retarded ED9.5 experimental embryos (D8.5_D9.5-1; left column), ED8.5 control embryos to 1-day retarded ED9.5 experimental embryos (C8.5_D9.5-1; 2nd column), ED8.5 control embryos to non-retarded ED8.5 experimental embryos (C8.5_D8.5; 3rd column), and ED7.5 control embryos to 1-day retarded ED8.5 experimental embryos (C7.5_D8.5-1; 4th column). Color intensity indicates stronger control, with blue and orange reflecting a negative and a positive Z-score, respectively, relative to the second term in the comparison. Note marked difference between 2nd and 3rd columns, which reflects the effect of growth retardation.
