Figure 3 | Scientific Reports

Figure 3

From: T-cell tolerance and exhaustion in the clearance of Echinococcus multilocularis: role of inoculum size in a quantitative hepatic experimental model

Figure 3

Hepatic inflammatory cell subsets in mice infected with different E. multilocularis PSC inocula during the course of infection. (a) Absolute quantification of hepatic CD4 (NK1.1−CD3+CD4+) T cells. (b) Absolute quantification of hepatic CD8 (NK1.1−CD3+CD8+) T cells. (c) The ratio of CD4 T cells / CD8 T cells in the liver. (d) Absolute quantification of hepatic NK (NK1.1+CD3−) cells. (e) Absolute quantification of hepatic NKT cells. (f) Absolute quantification of hepatic CD19 B cells. LD: 50 PSCs; MD: 500 PSCs; HD: 2000 PSCs. Data are shown as mean ± standard error of the mean (SEM, 5–6 mice per group), *p < 0.05, **p < 0.01 and ***p < 0.001.

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