Table 5 Hazard Ratios of sex for the cancer specific deaths of PTC.

From: Reevaluating the prognostic significance of male gender for papillary thyroid carcinoma and microcarcinoma: a SEER database analysis

Versions

Sex

Cancer Specific Deaths, No.

%

Cancer Specific Deaths per 1,000 Person–Years

95% CI

Unadjusted

Adjustment 1*

Adjustment 2†

Hazard Ratios

95% CI

p

Hazard Ratios

95% CI

p

Hazard Ratios

95% CI

p

All PTC

Female

117

0.35

1.76

1.46–2. 13

1 [Reference]

  

1 [Reference]

  

1 [Reference]

  

Male

107

1.06

5.42

4.44–6.62

3.09

2.38–4.02

<0.001

1.50

1.10–2.06

0.011

1.53

1.11–2.10

0.010

PTC > 1 cm

Female

109

0.57

2.91

2.39–3.54

1 [Reference]

  

1 [Reference]

  

1 [Reference]

  

Male

100

1.48

7.43

6.04–9.14

2.62

2.00–3.45

<0.001

1.46

1.05–2.02

0.024

1.52

1.09–2.11

0.014

PTMC

Female

8

0.06

0.23

0.10–0.52

1 [Reference]

  

1 [Reference]

  

1 [Reference]

  

Male

7

0.21

1.21

0.58–2.54

3.89

1.41–10.71

0.009

1.23

0.36–4.16

0.743

0.77

0.19–3.16

0.769

  1. PTC: Papillary thyroid cancer; PTMC: Papillary Thyroid Microcarcinoma.
  2. *Adjustment 1 was made for patient age at diagnosis, race, multifocality, tumor size, extrathyroidal invasion, lymph node metastasis and distant metastasis.
  3. †Adjustment 2 was made for patient age at diagnosis, race, multifocality, tumor size, extrathyroidal invasion, lymph node metastasis, distant metastasis, radiation and surgery treatment.
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