Table 2 Effect of PTT mixture and placebo supplementations for 14 days on platelet activation, haemostatic and inflammatory markers.

From: Effect of palm-based tocotrienols and tocopherol mixture supplementation on platelet aggregation in subjects with metabolic syndrome: a randomised controlled trial

 

PTT Mixture Intervention

Placebo Intervention

P

Activated glycoprotein IIb/IIIa receptor (MFI)

12.37 ± 3.42

12.09 ± 3.53

0.602

sP-selectin (ng/mL)

93.96 ± 67.53

78.60 ± 43.97

0.224

Fibrinogen (g/L)

3.00 ± 0.68

2.97 ± 0.69

0.865

D-dimer (ng/mL)

241.82 ± 170.72

287.80 ± 418.08

0.505

PAI-1 (ng/mL)

78.69 ± 33.91

80.11 ± 33.30

0.551

ucOC (ng/mL)

4.74 ± 2.10

4.90 ± 1.98

0.196

hsCRP (mg/L)

4.81 ± 4.86

4.94 ± 4.65

0.795

sE-selectin (ng/mL)

43.55 ± 15.02

43.45 ± 15.99

0.715

sICAM-1 (ng/mL)

220.20 ± 56.62

219.20 ± 63.68

0.629

sVCAM-1 (ng/mL)

554.60 ± 138.00

576.00 ± 149.00

0.210

  1. Prior to statistical analysis, data for activated glycoprotein IIb/IIIa receptor, fibrinogen, sE-selectin, sICAM-1 and hsCRP were logarithmic transformed. Data for activated glycoprotein IIb/IIIa receptor, fibrinogen, PAI-1, sE-selectin, sICAM-1 and hsCRP were analysed using Student t-test while data for D-dimer, ucOC, sP-selectin and sVCAM-1 were analysed using Wilcoxon Signed rank test. Abbreviation: hsCRP: high sensitivity C-reactive protein, PAI-1: plasminogen activator inhibitor type 1, sE-selectin: soluble E-selectin, sICAM-1: soluble intracellular adhesion molecules 1, sP-selectin: soluble P-selectin, sVCAM-1: soluble vascular cellular adhesion molecules 1, ucOC: undercarboxylated osteocalcin.
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