Table 4 Reactions added to the default Geant4-DNA chemical module27,28,29. The last reaction simulates the histone protein as an “absorber”: histone absorbs any molecule that directly touches it (no reaction rate is attributed to it).
From: Simulation of early DNA damage after the irradiation of a fibroblast cell nucleus using Geant4-DNA
Reaction | Reaction rate (109 M −1 · s −1) |
|---|---|
2-deoxyribose + OH • | 2.5 |
Adenine + OH • | 6.10 |
Guanine + OH • | 9.20 |
Thymine + OH • | 6.40 |
Cytosine + OH • | 6.10 |
Histone + molecule → histonemodified | — |
