Figure 1 | Scientific Reports

Figure 1

From: MiR-503 modulates epithelial-mesenchymal transition in silica-induced pulmonary fibrosis by targeting PI3K p85 and is sponged by lncRNA MALAT1

Figure 1

The expression of miR-503 is decreased in mouse lung tissues of silica-induced pulmonary fibrosis. (a) The sections were stained with hematoxylin and eosin as described in the materials and methods, which present the typical pathological alterations of pulmonary fibrosis. (b) Proteins of lung tissues were extracted and protein levels of EMT markers (E-cadherin, vimentin and α-SMA) were determined by western blot. Relative protein levels (means ± SD, n = 3) were analyzed by ImageJ, *P < 0.05 and **P < 0.01 versus the control group. (c) Total RNA of mouse lung tissues were extracted and relative miR-503 expression levels were examined by qRT-PCR, U6 was used as the interval reference, **P < 0.01 versus the control group.

Back to article page