Figure 2 | Scientific Reports

Figure 2

From: Rogdi Defines GABAergic Control of a Wake-promoting Dopaminergic Pathway to Sustain Sleep in Drosophila

Figure 2

Wake-promoting effects of Rogdi mutation require neither LD cycles nor the functionality of circadian rhythms. (a,b) Daily sleep profiles of control and Rogdi mutant flies in wild-type (a) or clock-less per 01 mutant backgrounds (b). Sleep behaviors in individual flies were monitored in LD cycles followed by constant dark (DD) cycles at 25 °C. Data represent average ± SEM (n = 35–126). (c,d) Daily sleep amount (top) and average sleep bout length (ABL, bottom) in LD (c) or the first DD (d) cycles were compared among control and Rogdi mutant flies in wild-type or per 01 mutant backgrounds. ***P < 0.001 to control or per 01 mutants as determined by one-way ANOVA, Tukey post hoc test.

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