Figure 2 | Scientific Reports

Figure 2

From: Gene Expression and Methylation Analyses Suggest DCTD as a Prognostic Factor in Malignant Glioma

Figure 2

The prognosis efficiency of DCTD. (A) The prognosis efficiency of DCTD in all WHO grade III and IV (except for the screening group, additional patients whose survival time is between 1 to 3 years were included, and the total number of samples was 178) patients in CGGA transcriptional microarray data and WHO grade III and IV glioma in CGGA RNA-seq data. (B) The prognosis efficiency of DCTD in GBM (n = 512) from TCGA transcriptional microarray data that were updated in 2013, which was expanded from the dataset that we used to search for the 7 genes and in GBM (n = 393) from TCGA RNA-seq dataset. (C) The prognosis efficiency of DCTD validated in GSE16011 and REMBRANDT datasets. (D) The ROC curves indicating the sensitivity and specificity of predicting 5 years of survival with DCTD-level in CGGA and TCGA database. (E) The ROC curves indicating the sensitivity and specificity of predicting 3 years of survival with DCTD-level in CGGA and TCGA database.

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