Table 2 TIC frequency of CD24, CD44 and EpCAM cells from xeno-B110 at fourth generation.
| Â | Cell Inoculation number | Number of tumours/Number of inoculated mice | |||||
|---|---|---|---|---|---|---|---|
CD24 | CD44 | EpCAM | |||||
br | dim | br | dim | br | dim | ||
xeno-B110 | 500 | 3/3 | 1/3 | 3/3 | 2/3 | 3/3 | 2/3 |
100 | 5/6 | 2/6 | 4/6 | 1/5 | 4/6 | 1/6 | |
10 | 1/6 | 0/6 | 2/6 | 0/6 | 0/6 | 0/6 | |
Estimated TIC frequency (CI) |  | 1 in 56 (23–135) | 1 in 591 (177–1971) | 1 in 67 (27–163) | 1 in 474 (149–1511) | 1 in 104 (42–261) | 1 in 509 (162–1605) |
p value | Â | <0.01 | <0.01 | 0.03 | |||
Enrichment factor (br/dim) | Â | 10.55 | 7.07 | 4.89 | |||
