Figure 5
Effects of oral propionate on subclinical changes in ileal gene expression in uveitis. (A) Relative expression of anti-microbial peptides and trefoil factor 3 (TFF3) in immunized vs non-immunized (NI) mice, and the effect of oral propionate (Prop) administration. (B) Relative expression of cytokines in immunized vs NI mice, and the effect of Prop administration. (C) Relative expression of the G-protein coupled receptor GPR43 in non-immunized vs. immunized EAU mice with or without propionate treatment. NaCl: sodium chloride treated groups; IFNγ: interferon-gamma; IL-10: interleukin-10; IL-17: interleukin-17. *p < 0.05, **p < 0.01, ***p < 0.001; n = 10–11 animals per treatment group, all values are expressed as mean ± SEM.
