Figure 5
From: Dermatophagoides pteronyssinus immunotherapy changes the T-regulatory cell activity
Changes induced by α-IL-10 and α-TGF-β blocking antibodies in different subpopulations of DP-specific Teff cells from DP-SCIT treated patients (N = 16). Bars represent different comparisons of IL-10 and TGF-β inhibitions performed in absence or presence of Tregs (from 0 or 12 months) on Th1 0 (A) and 12 months(B), Th2 0 (C) and 12 months (D) and Th9 0 (E) and 12 months (F). Statistical analysis was carried out by Wilcoxon test; p-values ≤ 0.05 are considered statistically significant. PI: proliferative index; 0 M: Treg cells obtained at 0 months; 12 M: Treg cells obtained at 12 months.
