Figure 2 | Scientific Reports

Figure 2

From: Zebrafish In-Vivo Screening for Compounds Amplifying Hematopoietic Stem and Progenitor Cells: - Preclinical Validation in Human CD34+ Stem and Progenitor Cells

Figure 2

Ex vivo VPA treatment preserves engraftment capacity of whole kidney marrow cells. (a) A representative plot showing gating strategy used to determine the degree of chimerism in the recipient and the FACS plot of PBS and VPA treated conditions. (b) PBS-treated control donor WKM cells failed to engraft the kidney of the recipient, but VPA treated cells demonstrated an engraftment capacity similar to that of freshly isolated cells (uncultured; n = 5 per group). Data are shown as mean ± SD, **p < 0.01, ***p < 0.001.

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