Table 1 LD50 values of dermatophytes against silkworms.

From: An invertebrate infection model for evaluating anti-fungal agents against dermatophytosis

Strains

LD50 ± SD (×105 germinated spore/silkworm)

A. vanbreuseghemii TIMM2789

9 ± 1

A. benhamiae IHEM20161

0.6 ± 0.1

M. canis 20080

2 ± 0.6

T. rubrum CBS118892

5 ± 2

  1. Germinated conidia were injected into the silkworm hemolymph, and the silkworms were reared at 30 °C. Survival of the animals was monitored after 72 hours (n = 5/group). LD50 values of dermatophytes were determined from three independent experiments.
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