Figure 1 | Scientific Reports

Figure 1

From: Expression and Differential Responsiveness of Central Nervous System Glial Cell Populations to the Acute Phase Protein Serum Amyloid A

Figure 1The alternative text for this image may have been generated using AI.

Treatment of rat cortical microglia with TNF-α or LPS up-regulates, in a time-dependent manner mRNA for Saa1 but not Saa3. (a) SAA1; (b) SAA3. Cultures of microglia were treated the day after plating (DMEM + 0.5% FCS) with 10 ng/ml TNF-α or 100 ng/ml LPS and processed 1, 3, 6 and 24 h later for qRT-PCR, as detailed in Methods. Data are presented as relative expression level (normalized with respect to β-actin (βACT)) at each time point for the control (untreated) cultures and are means ± s.e.m. n = 6. *p < 0.05 vs control (CTRL); **p < 0.01 vs control; ***p < 0.001 vs control. # p < 0.05 vs control and TNF-α; ## p < 0.01 vs control and TNF-α; ### p < 0.001 vs control.

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