Table 2 Proportion of LE-PAD according to tertile of distal aortic diameter in overall group and subgroups.
Lowest tertile | Median tertile | Highest tertile | P-value | P-value for trend | |
|---|---|---|---|---|---|
Overall | 288 (5.20%) | 164 (2.80%) | 155 (2.60%) | <0.001 | <0.0001 |
Sex | |||||
male | 112 (5.10%) | 54 (2.60%) | 56 (2.40%) | <0.001 | <0.0001 |
female | 176 (5.30%) | 110 (3.00%) | 99 (2.70%) | <0.001 | <0.0001 |
Age, yr | |||||
<65 | 78 (2.90%) | 62 (2.10%) | 63 (2.00%) | 0.03 | <0.0001 |
≥65 | 210 (7.40%) | 102 (3.70%) | 92 (3.30%) | <0.001 | <0.0001 |
Body mass index, kg/m2 | |||||
<25 | 161 (5.10%) | 70 (2.20%) | 59 (2.00%) | <0.001 | <0.0001 |
≥25 | 127 (5.40%) | 94 (3.60%) | 96 (3.10%) | <0.001 | <0.0001 |
MTHFR C677T polymorphisms | |||||
CC | 83 (5.30%) | 38 (2.40%) | 42 (2.50%) | <0.001 | <0.0001 |
CT | 149 (5.50%) | 86 (3.00%) | 78 (2.70%) | <0.001 | <0.0001 |
TT | 56 (4.40%) | 40 (3.00%) | 35 (2.50%) | <0.001 | <0.0001 |
Cigarette smoking | |||||
Never | 174 (4.80%) | 112 (2.70%) | 102 (2.50%) | <0.001 | <0.0001 |
Former | 35 (5.80%) | 13 (2.30%) | 12 (1.70%) | <0.001 | <0.0001 |
Current | 79 (6.20%) | 39 (3.50%) | 41 (3.50%) | 0.003 | <0.0001 |
Folic acid supplementation | |||||
No | 179 (5.30%) | 106 (3.00%) | 87 (2.40%) | <0.001 | <0.0001 |
Yes | 109 (5.10%) | 58 (2.60%) | 68 (2.80%) | <0.001 | <0.0001 |