Table 3 Biometric and plasma parameters in 90-day-old male offspring of rats supplemented with GSPE or vehicle during lactation.

From: Maternal intake of grape seed procyanidins during lactation induces insulin resistance and an adiponectin resistance-like phenotype in rat offspring

 

STD-veh

STD-GSPE

CAF-veh

CAF-GSPE

Two-way ANOVA

Biometric parameters

Initial body weight (g)

40 ± 2

41 ± 1

41 ± 1

42 ± 1

Final body weight (g)

373 ± 9

375 ± 8

446 ± 12

431 ± 13

D

Body weight gain (g)

333 ± 8

334 ± 7

405 ± 12

389 ± 12

D

Liver (g)

12.0 ± 0.4

11.6 ± 0.4

14.3 ± 0.5

13.8 ± 0.5

D

RWAT (g)

6.47 ± 0.45

8.33 ± 0.84

18.6 ± 1.7

17.7 ± 1.0

D

MWAT (g)

4.28 ± 0.27

5.00 ± 0.40

8.46 ± 0.57

9.03 ± 0.67

D

EWAT (g)

5.67 ± 0.48

7.29 ± 0.60

14.9 ± 1.3

15.2 ± 1.3

D

IWAT (g)

11.9 ± 1.0

13.0 ± 1.1

29.3 ± 3.0

28.00 ± 2.6

D

Adiposity index (%)

7.75 ± 0.54

9.02 ± 0.66

16.1 ± 1.0

16.3 ± 0.9

D

Gastrocnemius muscle (g)

1.74 ± 0.05

1.78 ± 0.06

1.86 ± 0.02

1.81 ± 0.04

Soleus muscle (g)

0.147 ± 0.006

0.147 ± 0.006

0.142 ± 0.04

0.143 ± 0.04

Lean mass (g)

322 ± 9

319 ± 8

332 ± 5

321 ± 8

Lean mass (%)

86.2 ± 0.8

85.0 ± 1.1

74.8 ± 1.4

74.6 ± 1.3

D

Fat mass (g)

32.0 ± 2.7

36.9 ± 4.2

93.1 ± 8.4

92.1 ± 7.1

D

Fat mass (%)

8.6 ± 0.8

9.8 ± 1.1

20.5 ± 1.4

21.1 ± 1.3

D

Plasma parameters

Total cholesterol (mmol/L)

1.65 ± 0.11

1.90 ± 0.13

2.20 ± 0.09

2.21 ± 0.09

D

Triglycerides (mmol/L)

1.75 ± 0.32

1.27 ± 0.18

3.67 ± 0.39

3.93 ± 0.22

D

NEFAs (mmol/L)

0.28 ± 0.04

0.23 ± 0.02

0.34 ± 0.02

0.33 ± 0.03

D

Phospholipids (mmol/L)

1.77 ± 0.09

1.90 ± 0.04

2.38 ± 0.12

2.60 ± 0.09

D

MCP-1 (ng/mL)

8.64 ± 0.37

8.92 ± 0.37

12.0 ± 0.4

11.1 ± 0.8

D

Leptin (ng/mL)

9.33 ± 0.63

9.49 ± 0.87

39.6 ± 3.6

41.8 ± 2.8

D

  1. Data are the mean ± SEM (n = 10–13). Two-way ANOVA analysis (2 × 2 factorial designs: diet (STD or CAF) × metabolic programming effect (vehicle or GSPE) was used to evaluate differences in these parameters. D: effect of the type of diet, (two-way ANOVA, p < 0.05). MWAT, mesenteric white adipose tissue.