Figure 1 | Scientific Reports

Figure 1

From: Sequence composition predicts immunoglobulin superfamily members that could share the intrinsically disordered properties of antibody CH1 domains

Figure 1

Variation of sequence properties in Fab fragment domains. Various properties are displayed for VH, CH1, VL, CL and CDR regions. CDR sequences were concatenated for each Fab to define one combined CDR sequence for each Fab fragment. Values are plotted as z-score deviations from population averages, using the population standard deviation. Population averages (Niwa) for the E. coli proteome28 are drawn at the zero deviation line. (a) Lysine – arginine composition. (b) Isoelectric point, pI. (c) Sequence entropy.

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