Figure 5
Neurodegenerative phenotypes in AKD mice. (A) Cresyl violet staining to (B) quantify the Nissl-positive cells and to detect the morphology in the Scr and AKD mouse hippocampal CA1, CA3 and DG regions. (C) Western blot analysis of neuronal nuclei (NeuN) and caspase 3 (Caspase 3) in Scr and AKD mice. (D) Densitometry analysis of NeuN and Caspase 3 (E) Cell viability and caspase 3/7 activity after 3 days of Scr and AdipoR1 shRNA transfection. Values indicate the mean ± SEM, n = 8–10, *P < 0.01, #P < 0.001, Student’s t-test.
