Figure 5
From: Modeling the Kinetics of Integrin Receptor Binding to Hepatic Extracellular Matrix Proteins
Kinetic simulations data. Model was initialized using ligand concentrations from proteomic analysis (Table 1) and kinetic rates listed in Table 2. The ECM:integrin binding pairs fibronectin:αvβ3, von Willebrand factor: αvβ3, and collagen I:α1β1 are shown, with binding curves and percent occupancy for fully occupied single divalent receptors (C d ) and aggregated receptor pairs (A dd ).
