Figure 5
From: Acinar cells in the neonatal pancreas grow by self-duplication and not by neogenesis from duct cells
Specific duct-labelling and absence of acinar-labelling in Hnf1bCreERT R26-YFP. Pancreas from TAM-treated Hnf1bCreERT R26R mice were double stained for X-gal - amylase (a,b) and X-gal - cytokeratin (c,d) at 1-week (a–c) and 4-weeks (b–d) of age. At both time points X-gal remained restricted to cytokeratin + duct cells and was absent from amylase + acinar cells. Shown are representative photomicrographs at original magnification of ×20.
