Figure 3

Suppression of BLA disulphide bond breakage by MMTS. (A) Size-exclusion HPLC elution profiles for BLA (20 µg) upon heating at 100 °C in the presence or absence of 1 mM MMTS. (B) SDS-PAGE analysis of BLA migration changes upon heating with or without thiol reactive reagents. All heating experiments were performed in HEPES buffer, pH 6.8.