Table 1 Univariate analysis of NCI vs. PSCI subjects in the model development dataset.
From: Development and validation of a risk score (CHANGE) for cognitive impairment after ischemic stroke
Variables | NCI N = 131 (62.68%) | PSCI N = 78 (37.32%) | p value |
|---|---|---|---|
Follow-up interval, mean (SD), days | 109.81 (96.34) | 124.70 (120.85) | 0.830 |
Age, mean (SD), years | 57.34 (11.45) | 68.94 (10.61) | <0.001* |
Gender, No. (%), female | 35 (26.72) | 32 (41.03) | 0.032* |
Education, mean (SD), years | 6.35 (4.39) | 1.63 (2.67) | <0.001* |
Education <6 years, No. (%) | 52 (39.69) | 67 (85.90) | <0.001* |
Race, No. (%) | 0.467 | ||
Chinese | 105 (80.15) | 68 (87.18) | |
Malay | 16 (12.21) | 4 (5.13) | |
Indian | 7 (5.34) | 5 (6.41) | |
Others | 3 (2.30) | 1 (1.28) | |
Diabetes mellitus, No. (%) | 55 (41.98) | 31 (39.74) | 0.750 |
Hypertension, No. (%) | 94 (71.76) | 69 (88.46) | 0.005* |
Hyperlipidemia, No. (%) | 103 (78.63) | 66 (84.62) | 0.287 |
Atrial fibrillation, No. (%) | 16 (12.21) | 17 (21.79) | 0.066 |
Smoking history, No. (%) | 45 (34.35) | 15 (19.48) | 0.006* |
History of TIA, No. (%) | 12 (9.16) | 3 (3.85) | 0.150 |
History of stroke, No. (%) | 21 (16.03) | 10 (12.82) | 0.528 |
History of IHD, No. (%) | 21 (16.03) | 19 (24.36) | 0.146 |
GCA score, mean (SD) | 0.34 (0.54) | 0.56 (0.66) | 0.009* |
Fazekas WMH score, mean (SD) | 1.31 (0.96) | 2.01 (0.80) | <0.001a |
Acute lacunar infarcts, mean (SD) | |||
Cortical | 1.10 (2.21) | 1.96 (3.55) | 0.326 |
Sublobar | 0.27 (0.69) | 0.21 (0.52) | 0.404 |
Infratentorial | 0.30 (0.81) | 0.37 (1.23) | 0.385 |
Acute non-lacunar infarcts, mean (SD) | |||
Cortical | 0.45 (0.82) | 0.85 (1.03) | <0.001* |
Sublobar | 0.14 (0.39) | 0.19 (0.46) | 0.363 |
Infratentorial | 0.07 (0.28) | 0.04 (0.19) | 0.474 |
Chronic infarcts, mean (SD) | |||
Cortical | 0.29 (0.72) | 0.60 (1.00) | 0.009* |
Sublobar | 0.49 (0.92) | 0.77 (1.13) | 0.022* |
Infratentorial | 0.21 (0.69) | 0.28 (0.66) | 0.187 |
