Figure 4 | Scientific Reports

Figure 4

From: IL-17A induces heterogeneous macrophages, and it does not alter the effects of lipopolysaccharides on macrophage activation in the skin of mice

Figure 4

Cytokine, CXCL2 and TNF-α mRNA expression in the skin of IMQ-treated B6 mice and the effects of IL-17A neutralization. Mouse recombinant anti-mouse IL-17A was administered intraperitoneally (50 μg) and IMQ was topically applied once a day for a week B6 mice. The mice were sacrificed, and the full thickness sections of the dorsal skin were dissected. Quantitative RT-PCR analysis of cytokine, CXCL2 and TNF-α mRNA expression in the skin of IMQ-treated and -untreated B6 mice (n = 4–6). *P < 0.005. NS: not significant. ND: no data.

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