Figure 7
From: Selective Homogeneous Assay for Circulating Endopeptidase Fibroblast Activation Protein (FAP)
Plasma FAP activity is completely suppressed in mice fed chow with cpd60. Ten to eighteen-week old C57/BL6 background mice were fed ad libitum control chow (blue circles), diet containing 20 ppm of cpd60 (green squares), or diet containing 100 ppm of cpd60 (red triangles). Plasma was isolated from blood retrieved at the indicated time points and FAP activity levels determined using the aP peptide. N = 5 animals per group. P values indicated were calculated by student t-test (****P < 0.0001 for 20 ppm cpd60 vs control diet; ####P < 0.0001 for 100 ppm cpd60 vs control diet).
