Table 1 Participant characteristics.
From: Vitamin D and cognitive function: A Mendelian randomisation study
Total | Males | Age, yrs | Age ≥ 65yrs | 25(OH)D, nmol/l | CYP2R1 , MAF | DHCR7 , MAF | |
|---|---|---|---|---|---|---|---|
N = 172,349 | (%) | (median, IQR) | (%) | (median, IQR) | (%) | (%) | |
Studies with 25(OH)D (N = 28,070) | |||||||
1958BC | 5,633 | 49·1 | 50 (NA) | 0 | 57·0 (33·9) | 43·0 | 22·2 |
CoLaus | 875 | 45·1 | 70 (6) | 100 | 47·3 (33·6) | 47·1 | 27·9 |
ESTHER | 8,080 | 43·0* | 74 (4)* | 100* | 45·1 (27·1) | 46·2 | 25·7 |
HBCS | 1,059 | 59·1 | 67·6 (3·6) | 91·8 | 61 (24) | 38·5 | 38·0 |
NFBC66 | 3,488 | 43·5 | 46·5 (0·9) | 0 | 50·2 (20·8) | 40·8 | 38·9 |
PIVUS | 891 | 50·3 | 70·1 (0·2) | 100 | 56 (26·5) | 39·9 | 35·0 |
Tromsø | 4,766 | 55·4 | 69 (11) | 76·8 | 56·5 (25·9) | 41·2 | 38·6 |
ULSAM | 1,118 | 100 | 71 (0·9) | 100 | 68·2 (24·7) | 39·4 | 33·4 |
YFS | 2,160 | 45·1 | 43 (9) | 0 | 57 (25) | 38·2 | 40·4 |
Studies without 25(OH)D (N = 144,279) | |||||||
ASPS | 780 | 43·3 | 64.7 (11) | 49·2 | NA | 43·7 | 29·3 |
ELSA | 5,382 | 45·6 | 65 (15) | 50·6 | NA | 43·2 | 22·4 |
HRS | 9,930 | 41·4 | 68 (15) | 62 | NA | 43·8 | 27·0 |
STR | 969 | 44·7 | 72.1 (10·1) | 77·2 | NA | 38·8 | 30·0 |
TwinGene | 2,362 | 51·1 | 69 (6) | 100 | NA | 40·0 | 33·2 |
UKBiobank | 111,936 | 47·5 | 58 (12) | 19·7 | NA | 42·2 | 21·0 |
UKHLS | 8,577 | 43·7 | 54 (24) | 28·0 | NA | 42·4 | 21·6 |
WII | 4,343 | 76·2 | 59·7 (10) | 28·7 | NA | 42·5 | 22·7 |
