Figure 7 | Scientific Reports

Figure 7

From: Prokineticin receptor-1-dependent paracrine and autocrine pathways control cardiac tcf21+ fibroblast progenitor cell transformation into adipocytes and vascular cells

Figure 7

Prokineticin/PKR1 signaling drives tcf21+ cell fate. Schematic illustration showing that PKR1 signaling in tcf21+ CPFs suppresses fibroblast-adipocytes-transformation and promotes fibroblast-vasculogenic-transformation via autocrine and paracrine pathways through prokineticin-2 following consumption of a high-fat diet (HFD). The drawings were created using Servier Medical Art illustration resources (www.servier.com).

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