Table 1 Patient characteristics according to ISS.

From: The international staging system improves the IPI risk stratification in patients with diffuse large B-cell lymphoma treated with R-CHOP

Characteristics

N (%)

ISS

P-value

I (n = 90)

II(n = 98)

III(n = 27)

Gender

    

0.688

 Female

141(65.6%)

62(68.9%)

62(63.3%)

17(63.0%)

 

 Male

74(34.4%)

28(31.1%)

36(36.7%)

10(37.0%)

 

Age(years)

    

0.609

 <60 y

175(81.4%)

76(84.4%)

78(79.6%)

21(77.8%)

 

 ≥60 y

40(18.6%)

14(15.6%)

20(20.4%)

6(22.2%)

Systemic symptoms

    

0.011

 A

143(66.5%)

70(77.8%)

56(57.1%)

17(63.0%)

 

 B

72(33.5%)

20(22.2%)

42(42.9%)

10(37.0%)

IPI score

    

0.001

 0–2

157(73.0%)

70(77.8%)

73(74.5%)

14(51.9%)

 

 3–5

58(27.0%)

20(22.2%)

25(25.5%)

13(48.1%)

Performance status

    

0.239

 0–1

152(70.7%)

66(73.3%)

71(72.4%)

15(55.6%)

 

 2–4

63(29.3%)

24(26.7%)

25(27.6%)

11(44.4%)

Lactate dehydrogenase

    

0.019

 Normal

101(47.0%)

50(55.6%)

44(44.9%)

7(25.9%)

 

 High

114(53.0%)

40(44.4%)

54(55.1%)

20(74.1%)

Ann Arbor stage

    

0.082

 I or II

89(41.4%)

44(48.9%)

38(38.8%)

7(25.9%)

 

 III or IV

126(58.6%)

46(51.1%)

60(31.2%)

20(74.1%)

No. of extranodal sites

    

0.112

 0–1

113(52.6%)

54(60.0%)

44(44.9%)

15(55.6%)

 

 ≥2

102(47.4%)

36(40.0%)

54(55.1%)

12(44.4%)

Cell-of-origin subtype

    

0.819

 GCB

48(22.3%)

23(33.3%)

20(33.9%)

5(26.3%)

 

 NON-GCB

99(46.0%)

46(66.7%)

39(66.1%)

14(73.7%)

Treatment

    

 CHOP

78(36.3%)

30(33.3%)

43(43.9%)

5(18.5%)

0.899

 R-CHOP

137(63.7%)

60(66.7%)

55(56.1%)

22(81.2%)