Table 6 Results for the gene-set enrichment analysis.

From: Exhaustive search for epistatic effects on the human methylome

Term

Pathway

N genes

N hits

p nominal

p FDR

hsa05165

Human papillomavirus infection

303

10

1.7 × 10−7

0.0014

hsa05200

Pathways in cancer

384

10

1.1 × 10−6

0.0036

hsa05224

Breast cancer

141

7

1.5 × 10−6

0.0036

hsa01100

Metabolic pathways

1190

14

1.7 × 10−6

0.0036

hsa04014

Ras signaling pathway

217

7

9.9 × 10−6

0.017

hsa04151

PI3K-Akt signaling pathway

317

8

1.2 × 10−5

0.018

hsa05203

Viral carcinogenesis

191

6

2.9 × 10−5

0.036

  1. Significant gene-sets (p FDR  < 0.05) are reported.