Figure 2
From: Unveiling some FDA-approved drugs as inhibitors of the store-operated Ca2+ entry pathway
Concentration-response curves demonstrating the dose-dependence of inhibitory effect of indicated drugs and BTP2 on the SOCE in RBL-1 cells triggered by Thapsigargin. SOCE was denoted by the peak Fura-2 fluorescence ratio following Ca2+ add back during Ca2+ imaging experiment of RBL-1 cells loaded with Fura-2AM. Each value (mean ± SEM) was derived from 3–5 individual experiments and a total of 60–100 cells.
