Table 3 Cell-number–dependent effects of DPC-FS transplantation on locomotor recovery (BBB scores).

From: Priming with FGF2 stimulates human dental pulp cells to promote axonal regeneration and locomotor function recovery after spinal cord injury

 

Vehicle (n = 5)

1 × 104 (n = 6)

1 × 105 (n = 5)

1 × 106 (n = 5)

1 W

0.1 ± 0.1

0.3 ± 0.1

0.9 ± 0.2

0.7 ± 0.4

3 W

0.9 ± 0.3

0.8 ± 0.3

3.5 ± 1.0*

4.0 ± 0.8**

7 W

0.5 ± 0.3

0.9 ± 0.4

4.4 ± 1.0***

4.9 ± 0.9***

  1. Locomotor function of the hind limbs was evaluated at 1, 3, and 7 weeks after injury and transplantation with the indicated number of DPC-FS. The values are expressed as the mean ± SE. Significant differences were determined using two-way repeated measures ANOVA with a post hoc Tukey’s multiple comparison test; *p < 0.05, **p < 0.01, and ***p < 0.001 compared with the SCI/vehicle group.
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