Table 4 Effects of short-term FGF2 withdrawal or supplementation on locomotor recovery in SCI rats after DPC transplantation (BBB scores).

From: Priming with FGF2 stimulates human dental pulp cells to promote axonal regeneration and locomotor function recovery after spinal cord injury

 

DPC-S (n = 10)

DPC-S/FS1 hr (n = 5)

DPC-FS (n = 10)

DPC-FS/S1 day (n = 6)

1 W

1.3 ± 0.3

0.2 ± 0.1

0.7 ± 0.3

0.3 ± 0.3

3 W

1.7 ± 0.3

1.6 ± 0.3

3.5 ± 0.6*

3.8 ± 0.7*

7 W

2.6 ± 0.5

2.7 ± 0.6

5.0 ± 0.5***

5.3 ± 0.9***

  1. Locomotor function of the hind limbs was evaluated at 1, 3, and 7 weeks after injury and transplantation of DPCs. The values are expressed as the mean ± SE. For statistical comparison, the data for DPC-S and DPC-FS were replotted from Fig. 2; *p < 0.05; ***p < 0.005 vs SCI/DPC-S (two-way ANOVA, post hoc with Tukey’s test).
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