Figure 4 | Scientific Reports

Figure 4

From: A role for the purinergic receptor P2X3 in astrocytes in the mechanism of craniofacial neuropathic pain

Figure 4The alternative text for this image may have been generated using AI.

Immunofluorescent staining for P2X3 (a,b), area occupied by P2X3-immunoreactivity (IR: c), intensity of P2X3-IR (d) and Western blot analysis for P2X3 protein level (e,f) in CCI-ION rats and sham rats. The area of immunostaining for P2X3, the intensity of P2X3-IR, and the P2X3 protein levels are increased significantly in the CCI-ION rats, compared to sham rats. Asterisks indicate significant difference between CCI-ION rats and sham rats (unpaired Student’s t-test; *P < 0.05, ***P < 0.001). Scale bar in B = 50 μm. N = 3 animals per group in immunohistochemical analysis (a–d). N = 4 animals per group in Western blot analysis (e,f).

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