Table 1 Summary ORs for the Association of prothrombin G20210A SNP with Myocardial Infarction.
Variables | Overall | Ethnicity | Subgroups | |||
|---|---|---|---|---|---|---|
Caucasian | Non-Caucasian | ≤55 yo | >55 yo | |||
Allele model | OR | REM 1.43 | REM 1.40 | FEM 1.51 | REM 1.76 | REM 1.43 |
(95%CI) | (1.18–1.72) | (1.14–1.72) | (1.06–2.14) | (1.32–2.35) | (0.84–2.43) | |
p value | 0.0002 | 0.0012 | 0.022 | 0.0001 | 0.18 | |
I2 (%), | 39.7 | 45.2 | 14.6 | 42.6 | 52.7 | |
Phet | 0.01 | 0.01 | 0.31 | 0.02 | 0.1 | |
Homozygote model | OR | FEM 1.42 | FEM 1.48 | ND | FEM 1.77 | FEM 3.45 |
(95%CI) | (0.58–3.48) | (0.58–3.78) | (0.51–6.18) | (0.39–30.86) | ||
p value | 0.45 | 0.41 | ND | 0.37 | 0.27 | |
I2 (%), | 0 | 0 | ND | 0 | 0 | |
Phet | 0.98 | 0.95 | ND | 0.9 | 0.73 | |
Heterozygote model | OR | REM 1.41 | REM 1.37 | FEM 1.51 | REM 1.70 | FEM 1.34 |
(95%CI) | (1.16–1.72) | (1.11–1.70) | (1.05–2.15) | (1.24–2.33) | (0.98–1.84) | |
p value | 0.0007 | 0.0039 | 0.0244 | 0.0011 | 0.07 | |
I2 (%), | 35.4 | 38.8 | 19.3, | 36.4, | 40.9 | |
Phet | 0.03 | 0.04 | 0.27 | 0.06 | 0.17 | |
Dominant model | OR | REM 1.41 | REM 1.37 | FEM 1.52 | REM 1.70 | FEM 1.35 |
(95%CI) | (1.15–1.72) | (1.10–1.69) | (1.06–2.16) | (1.24–2.34) | (0.99–1.85) | |
p value | 0.0007 | 0.0045 | 0.022 | 0.001 | 0.06 | |
I2 (%), | 36.7, | 40.1 | 20.8 | 36.8, | 48.2, | |
Phet | 0.02 | 0.03 | 0.26 | 0.05 | 0.12 | |
Recessive model | OR | FEM 1.39 | FEM 1.46 | ND | FEM 1.73 | FEM 3.31 |
(95%CI) | (0.56–3.42) | (0.57–3.72) | (0.50–6.04) | (0.37–29.90) | ||
p value | 0.48 | 0.43 | ND | 0.39 | 0.29 | |
I2 (%), | 0 | 0 | ND | 0 | 0 | |
Phet | 0.98 | 0.95 | ND | 0.91 | 0.75 | |
