Figure 7
Effect of anti-PLAC1-ADC on induction of apoptosis in prostate cancer cells. Primary cultures of isolated epithelial cells of three human prostate cancer tissues were prepared and the level of PLAC1 expression was tested by flow cytometry (a). Pro-apoptotic activity of anti-PLAC1-ADC on LNCaP cells and human primary prostate cancer cells was assessed by Annexin V/Propidium Iodide (PI) apoptosis Assay (b). The results are representative of three experiments.
