Table 2 ROC curves of HPT+/AAAD+ patients and HPT+/AAAD− individuals in blinded trail set.

From: Characterization of serum miRNAs as molecular biomarkers for acute Stanford type A aortic dissection diagnosis

Risk score

AUC (95% CI)

P-value

Cutoff point

Sensitivity

Specificity

PV+

PV−

4-miR panel

0.973 (0.918–1.000)

<0.001

36.89%

93.33%

86.67%

87.50%

92.86%

miR-25

0.987 (0.937–1.000)

<0.001

1.353

86.67%

93.33%

92.86%

87.50%

miR-29a

0.951(0.856–1.000)

<0.001

1.354

93.33%

93.33%

93.33%

93.33%

miR-155

0.764 (0.576–0.952)

0.014

1.457

73.33%

86.67%

84.62%

76.47%

miR-26b

0.822(0.668–0.977)

0.003

0.500

73.33%

86.67%

84.62%

76.47%

  1. ROC: receiver operating characteristic; HPT: hypertension; AAAD: acute Stanford type A aortic dissection; AUC, area under curves; CI, confidence interval; PV+, positive predictive value; PV−, negative predictive value.
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