Table 3 Pathways and functional terms enriched for AD-DEGs.

From: Identification of molecular alterations in leukocytes from gene expression profiles of peripheral whole blood of Alzheimer’s disease

ID

Name

Hit Genes

P-value

KEGG

hsa00190

Oxidative phosphorylation

ATP5I, ATP5J, NDUFA1, UQCRB, ATP6V1G1, ATP5L, UQCRQ

6.63 × 10−5

hsa03010

Ribosome

RPL26, RPL31, RPS27A, MRPL21, MRPL22, MRPL33

6.62 × 10−4

hsa03050

Proteasome

PSMA2, PSMA3, PSMA4, POMP

5.15 × 10−3

Gene ontology

molecular function

  GO:0003735

structural constituent of ribosome

RPL26, RPL31, RPS27A, MRPL21, MRPL22, MRPL33, MRPL51

2.43 × 10−4

  O:0003723

RNA binding

RPF1, LARP7, RPL31, C14orf166, ZMAT2, RPL26, MRPL21, SSB, CWC15, EIF3D

1.18 × 10−3

cellular component

  GO:0005743

mitochondrial inner membrane

ATP5J, ATP5I, MRPL22, UQCRB, ATP5L, MRPL21, MRPL51, NDUFA1, UQCRQ

2.25 × 10−4

  GO:0019773

proteasome core complex,

PSMA2, PSMA3, PSMA4, POMP

8.89 × 10−4

biological process

  GO:0060071

Wnt signaling pathway

PSMA2, PSMA3, PSMA4, RPS27A PSMD10

9.50 × 10−4

  GO:0006412

translation

RPL26, RPL31, RPS27A, MRPL21, MRPL22, MRPL33, MRPL51

3.57 × 10−3

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