Figure 3
Screening results of the aptamer candidates against cell-SELEX cell lines using flow cytometry. (A) Screening results of MGB2 aptamers show six aptamers out of twelve (MAMB0, MAMB1, MAMB4, MAMB8, MAMB12, MAMB57) with higher fluorescence intensity in the target selection cell line than counter selection ones. (B) Screening results of MGB1 aptamers show four aptamers out of eight (MAMA2, MAMA5, MAMA6, and MAMA12) with higher fluorescence intensity in the target selection cell line than counter selection ones. Promising aptamers were chosen for further studies. The experiments were repeated twice. Values are shown as means ± S.E.M.
