Figure 2
From: Herpud1 negatively regulates pathological cardiac hypertrophy by inducing IP3 receptor degradation
Herpud1-KO mice develop cardiac hypertrophy. (a) Four-chamber image, 40X, with hematoxylin and eosin staining (n = 3). (b) Representative images (400X) of paraffin embedded cardiac tissue stained with wheat germ agglutinin (WGA) and quantification of cardiomyocyte cross-sectional area (n = 6). (c) Heart weight/body weight (mg g−1, n = 12). (d) Heart weight/tibia length (mg cm−1, n = 12). (e) Left and right ventricular plus septum weight/tibia length (mg cm−1, n = 6). (f) Left and right atrial weight/tibia length−1 (mg cm−1, n = 6) in wild-type (WT) and Herpud1-knockout (Herpud1-KO) 10-to-12-week-old mice. Mean ± SEM, analyzed using a t-test. *p < 0.05 vs. WT.
