Figure 3
From: Herpud1 negatively regulates pathological cardiac hypertrophy by inducing IP3 receptor degradation
Herpud1-KO mice develop myocardial dysfunction. (a) Representative long-axis echocardiography images, 2D and M-mode, of the left ventricle. LV: Left ventricle, Pap: papillary muscle. (b) % Fractional shortening (n = 12). (c) % Ejection fraction (n = 12). (d) Stroke volume (n = 12) in wild-type (WT) and Herpud1-knockout (Herpud1 KO) 10-to-12-week-old mice. Mean ± SEM, analyzed using a t-test. *p < 0.05 vs. WT.
