Figure 6 | Scientific Reports

Figure 6

From: Tripalmitin nanoparticle formulations significantly enhance paclitaxel antitumor activity against breast and lung cancer cells in vitro

Figure 6

Rhodamine assay in resistant HCT-15 cell line. (A) Flow cytometry analysis after exposure of HCT-15 cells to Rhodamine and Rhodamine together with Verapamil, Tripalm-NPs and Tripalm-NPs-MAC. Verapamil and NPs were added 24 hours before the addition of Rhodamine. Rhodamine retention was measured at different times. Data represent the mean value ± SD of quadruplicate experiences. Mean fluorescence are expressed in arbitrary units (AU). (B) Representative fluorescent images of Rhodamine retention into HCT-15 cells nonpretreated (a) and pretreated with Verapamil (b), Tripalm-NPs (c) and Tripalm-NPs-MAC (d). Pretreatment was carried out 24 hours before Rhodamine exposure. Rhodamine was observed in green. Nuclei were stained in blue. Scale bar = 10 µm.

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