Table 1 Clinical parameters for the classification of dry eye disease and control patients at each proteomic analysis.
From: Proteomic analysis of human lacrimal and tear fluid in dry eye disease
Specific step of proteomics analysis | Group | No. of Patients (female, n) | Age (years) | Schirmer test I (mm) | Tear breakup time (s) | Protein concentration (μg/μl) |
|---|---|---|---|---|---|---|
Global profiling | DED | 5 (4) | 62.20 ± 8.67 | 5.80 ± 1.30 | 3.40 ± 1.14 | TF: 11.86 ± 2.10 |
LF: 11.02 ± 1.04 | ||||||
Control | 5 (4) | 61.80 ± 7.79 | 13.80 ± 1.64 | 8.20 ± 0.84 | TF: 9.79 ± 0.84 | |
LF: 10.59 ± 1.90 | ||||||
MRM assay | DED | 17 (13) | 60.92 ± 9.01 | 5.76 ± 1.52 | 3.58 ± 0.87 | TF: 13.06 ± 1.81 |
LF: 11.44 ± 1.19 | ||||||
Control | 17 (13) | 61.06 ± 7.91 | 11.47 ± 2.00 | 7.89 ± 1.26 | TF: 11.78 ± 4.90 | |
LF: 11.69 ± 3.69 |