Table 4 Molecular changes in the IM - Comparison of molecular events between the control and AG groups.

From: Effects of long-term aspirin use on molecular alterations in precancerous gastric mucosa in patients with and without gastric cancer

No. of biopsy specimens

Control

AG group

P

n = 33

(%)

n = 16

(%)

MSI

5

(15.2)

2

(12.5)

1

CIMP

9

(27.3)

0

(0)

0.02

CDH1

7

(21.2)

1

(6.3)

0.25

CDKN2A

1

(3.0)

0

(0)

1

MLH1

0

(0)

0

(0)

1

MGMT

0

(0)

1

(6.3)

0.33

MINT1

23

(69.7)

12

(75.0)

1

MINT31

16

(48.5)

8

(50.0)

1

RUNX3

12

(36.4)

2

(12.5)

0.10

  1. IM, intestinal metaplasia; AG, atrophic gastritis; MSI, microsatellite instability; CIMP, CpG island methylator phenotype.
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