Table 5 Molecular changes in the IM - Comparison of molecular events between the AG and GC groups.

From: Effects of long-term aspirin use on molecular alterations in precancerous gastric mucosa in patients with and without gastric cancer

No. of biopsy specimens

AG group

GC group

P

n = 16

(%)

n = 27

(%)

MSI

2

(12.5)

5

(18.5)

0.69

CIMP

0

(0)

6

(20.0)

0.08

CDH1

1

(6.3)

4

(13.3)

0.64

CDKN2A

0

(0)

0

(0)

1

MLH1

0

(0)

0

(0)

1

MGMT

1

(6.3)

1

(3.3)

1

MINT1

12

(75.0)

19

(63.3)

0.52

MINT31

8

(50.0)

14

(46.7)

1

RUNX3

2

(12.5)

10

(33.3)

0.17

  1. IM, intestinal metaplasia; AG, atrophic gastritis; GC, gastric cancer; MSI, microsatellite instability; CIMP, CpG island methylator phenotype.