Figure 4
From: Evidence for Stress-like Alterations in the HPA-Axis in Women Taking Oral Contraceptives
OC intake and clinical questionnaire scores (n = 230 for BDI-II, n = 200 for CTQ). (A) Scatter plot BDI-II scores (y-axis) vs. circulating cortisol levels (X-axis) with corresponding regression lines stratified for OC intake. The slopes of the regression lines were significantly different (b = 2.98, 95%-CI: (0.32; 5.64), p = 0.028). (B) Box plots for BDI-II scores stratified for OC intake and rs1360780 genotype with no interaction present between OC intake and the rs1360780 genotype (b = −0.05, 95%-CI: (−5.09; 4.98), p = 0.984). (C) Scatter plot CTQ scores (y-axis) vs. circulating cortisol levels (X-axis) with corresponding regression lines stratified for OC intake. The slopes of the regression lines were not significantly different (b = 1.01, 95%-CI: (−4.12; 6.14), p = 0.699). (D) Box plots for CTQ scores stratified for OC intake and rs1360780 genotype with no interaction present between OC intake and the rs1360780 genotype (b = 0.31, 95%-CI: (−7.06; 7.68), p = 0.934).
