Table 1 Demographic characteristics of study subjects.

From: Genetic association study identified a 20 kb regulatory element in WLS associated with osteoporosis and bone mineral density in Han Chinese

 

Discovery (N = 2,549)

Replication (N = 4,071)

Case

Control

Case

Control

Subjects

859

1,690

1,039

3,032

Female/Male

578/281

1134/556

608/431

1780/1252

Age, years (sd)

61.54 (8.08)

61.18 (7.73)

62.32 (6.57)

62.21 (6.64)

BMI, kg/m2 (sd)

23.87 (1.50)

23.62 (1.41)

24.11 (1.43)

23.84 (1.34)

LS-BMD, g/cm2 (sd)

0.763 (0.07)

0.931 (0.06)

0.866 (0.10)

0.942 (0.07)

FN-BMD, g/cm2 (sd)

0.643 (0.07)

0.852 (0.05)

0.772 (0.12)

0.872 (0.06)

OPG, pg/ml (sd)

130.07 (25.42)

178.31 (27.68)

158.82 (35.31)

175.23 (26.71)

sRANKL, pg/ml (sd)

14.76 (4.22)

11.40 (2.52)

12.71 (3.65)

11.49 (2.75)

  1. BMI, body mass index; BMD, bone mineral density; LS, lumbar spine; FN, femoral neck; OPG, osteoprotegerin; sRANKL, soluble receptor activator of nuclear factor-JB ligand.
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