Figure 2 | Scientific Reports

Figure 2

From: Calcineurin/P-ERK/Egr-1 Pathway is Involved in Fear Memory Impairment after Isoflurane Exposure in Mice

Figure 2

The influence of isoflurane on CaN in hippocampus and amygdala. No change of CaN protein expression is detected at different time points post isoflurane exposure in hippocampus (A: P > 0.05) and Amygdala (B: P > 0.05). Results were normalized against the mock training + Air group. The dephosphorylation efficacy of CaN, is markedly increased by isoflurane, it increased at 2 h after exposure, peaked at 8 h, persisted in a high level at 48 h, and went down to air group level 7 days after isoflurane exposure in both hippocampus and amygdala (C). *P < 0.05, ***P < 0.01, ***P < 0.001 compared with Iso group. n = 5~7 for each group.

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