Table 5 Risk association between frequency of blood lymphocytes with X chromosomal aneuploidy and bladder cancer risk, Female Only.

From: Strong associations between chromosomal aberrations in blood lymphocytes and the risk of urothelial and squamous cell carcinoma of the bladder

No. of lymphocytes with X chromosome aneuploidy

Case

Control

OR

(95% CI)

p-for-trend

All subject

0

35

44

ref

  

1

44

54

0.96

(0.48–1.93)

 

>=2

26

21

1.13

(0.48–2.67)

0.92

Age <= 60

0

27

34

ref

  

1

28

38

0.54

(0.22–1.31)

 

>=2

18

10

1.41

(0.45–4.39)

0.18

Age> 60

0

8

10

ref

  

1

16

16

1.95

(0.48–7.84)

 

>=2

8

11

0.65

(0.13–3.42)

0.31

 

Case (SCC)

Control

OR

(95% CI)

p-for-trend

All subject

0

9

44

ref

  

1

21

54

1.69

(0.59–4.86)

 

>=2

10

21

2.05

(0.58–7.25)

0.49

Age <= 60

0

6

34

ref

  

1

16

38

1.45

(0.41–5.06)

 

>=2

8

10

2.53

(0.53–12.18)

0.51

Age> 60

0

3

10

ref

  

1

5

16

2.37

(0.25–22.40)

 

>=2

2

11

0.82

(0.04–15.96)

0.61

 

Case (UC)

Control

OR

(95% CI)

p-for-trend

All subject

0

25

44

ref

  

1

22

54

0.66

(0.30–1.45)

 

>=2

14

21

0.76

(0.28–2.05)

0.58

Age <= 60

0

20

34

ref

  

1

12

38

0.35

(0.12–0.96)

 

>=2

8

10

1.04

(0.29–3.77)

0.09

Age >60

0

5

10

ref

  

1

10

16

1.51

(0.32–7.03)

 

>=2

6

11

0.50

(0.07–3.33)

0.43

  1. SCC = Squamous cell carcinoma; UC = urothelial carcinoma; CI = confidence interval; ORs were adjusted for age, gender, BMI, smoking status and education.