Table 6 Risk association between frequency of blood lymphocytes with Y chromosome aneuploidy and bladder cancer risk, Male Only.

From: Strong associations between chromosomal aberrations in blood lymphocytes and the risk of urothelial and squamous cell carcinoma of the bladder

No of lymphocyte with Y chromosome aneuploidy

Case

Control

OR

(95% CI)

p-for-trend

All subject

0

264

307

ref

  

1

122

96

1.47

(1.02–2.12)

 

>=2

42

38

1.31

(0.74–2.31)

0.10

Age <= 60

0

148

155

ref

  

1

58

40

1.46

(0.83–2.56)

 

>=2

10

11

0.58

(0.18–1.84)

0.23

Age >60

0

116

152

ref

  

1

64

56

0.10

(0.93–2.47)

 

>=2

32

27

0.22

(0.89–3.32)

0.11

SCC cases only

Case(SCC)

Control

OR

(95% CI)

p-for-trend

0

49

307

ref

  

1

28

96

2.56

(1.36–4.82)

 

>= 2

8

38

1.35

(0.49–3.71)

0.01

Age <= 60

0

30

155

ref

  

1

18

40

2.99

(1.29–6.97)

 

>=2

2

11

0.63

(0.09–4.26)

0.02

Age >60

0

19

152

ref

  

1

10

56

2.93

(1.05–8.21)

 

>=2

6

27

2.08

(0.57–7.57)

0.10

UC cases only

Case(UC)

Control

OR

(95% CI)

p-for-trend

0

208

307

ref

  

1

92

96

1.31

(0.89–1.92)

 

>=2

33

38

1.25

(0.69–2.26)

0.36

Age <= 60

0

112

155

ref

  

1

39

40

1.21

(0.66–2.25)

 

>=2

7

11

0.54

(0.15–1.95)

0.49

Age >60

0

96

152

ref

  

1

53

56

1.40

(0.85–2.33)

 

>=2

26

27

1.65

(0.84–3.25)

0.21

  1. SCC = Squamous cell carcinoma; UC = urothelial carcinoma; CI = confidence interval; ORs were adjusted for age, gender, BMI, smoking status and education.